Medicine Health

Summary

Complex intracellular inclusions were identified in brain cells of patients with non-inflammatory stealth virus encephalopathy. The cells showed extensive disruption of mitochondria leading to the suggestion that the inclusions were providing an alternative (non-mitochondria) source of cellular energy. Pigmented intracellular inclusions and extra-cellular materials were similarly identified in stealth virus cultures.

A characteristic feature of these cultures is the progressive lessening of the cytopathic (cell damaging) effect that coincides with, and is dependent upon, the accumulation of these pigmented materials. Tissue culture and direct patient derived materials exhibit various qualities consistent with their functioning as energy transducers. Specifically, they are composed of conglomerates of finer particles that can display fluorescent, electrostatic, sound resonating and variable magnetic activities. Individual particles contain various combinations of different minerals. They can act as both electron donors and electron acceptors in redox reactions and can also generate gas bubbles from water.

The viability of cells in cultures containing alternative cellular energy pigments (ACE-pigments) can be influenced by exposure to external electromagnetic, magnetic and sound frequencies that have no discernable effects on normal cell cultures. Enhanced cell growth and survival occurs upon exposure to relatively low intensities, while cell destruction occurs at higher intensity external energy exposure. Various natural products show ACE-pigment like activities, including a capacity of protecting cell cultures from the cytopathic effect of stealth viruses. These products are suitable for double blind clinical studies.

Introduction

Plants and certain bacteria derive energy in the form of sunlight to covalently link hydrogen and carbon atoms to form carbohydrates. This photosynthetic process is mediated by chlorophyll molecules that can specifically absorb photons corresponding to the blue and red components of sunlight. The photons elevate the energy levels of particular electrons within the chlorophyll molecules that can then be used in an electron donating (reducing) reaction between carbon dioxide and water to yield carbohydrates, such as glucose.

Electrons can subsequently be withdrawn from carbohydrates in the form of chemical energy for synthesis of other types of life sustaining organic molecules and for the generation heat. Protons typically accompany electrons in electron donating (reduction) and electron capturing (oxidation) reactions. The term oxidation is used since oxygen plays a major role as an electron acceptor to form water.

Chlorophyll utilizes only a minor fraction of the entire electromagnetic spectrum. Not only does this seem rather inefficient but the question can also be asked what was the energy used to synthesize the original chlorophyll molecules. Energy could conceivably be derived from other parts of the electromagnetic spectrum and/or from other less well understood forms of energy.

Viruses can cause cell damage by various mechanisms including simple competition for the metabolic resources available to the cell. I have defined a grouping of cytopathic (cell damaging) viruses, termed stealth viruses, that fail to evoke an immune mediated inflammatory reaction (please refer to http://www.s3support.com for a complete list of publications). The best characterized stealth virus originated from the cytomegalovirus of African green monkeys. The virus was isolated from a patient with the chronic fatigue syndrome, with a similar but not identical virus isolated from a patient with a manic depressive, bi-polar illness.

The virus induces a severe acute disease in cats followed by considerable clinical recovery in spite on an absent inflammatory response. Similarly, the cytopathic effect in tissue culture tends to abate over time, especially in infrequently fed cultures. The mechanism of this striking recovery process is attributed to materials that accumulate in tissue culture supernatants since reactivation occurs upon replacing the tissue culture medium with fresh medium. Reactivation can be prevented by including supernatant materials from repaired cultures into the re-feeding medium.

Unusual intracellular and extra-cellular materials were previously noted in the brains of stealth virus inoculated cats and in the brain biopsies of various patients with stealth virus encephalopathy. They were periodic acid Schiff (PAS) positive and also readily seen using the cationic Stains-all dye.

Irregularly shaped inclusions were also noted on electron microscopy of both animal and human brain biopsies. The highly ordered complex structures of some of these inclusions suggested that they were fulfilling some cellular function. Given the marked disruption of the cells' mitochondria, it seemed reasonable to postulate that the inclusions may be providing an alternative (non-mitochondria) energy source. The following data support such a conclusion.

Complex Inclusions in a Brain Biopsy from a Stealth Virus Infected Child

The child's illness evolved over seven months from what was initially considered to be a conduct and attention deficit disorder to an apparent neurological disease. In spite of markedly abnormal magnetic resonance imaging (MRI), his early neurological examination was essentially normal. A brain biopsy showed lipid accumulation within glial cells without accompanying inflammation, and was considered non-diagnostic by the attending and referral neuropathologists.

After extensive clinical reviews in major medical centers, a second brain biopsy was performed at Stanford University , this time with sections prepared for electron microscopy. Apart form the lipid vacuolization and mitochondria damage, the attending neuropathologist failed to report on any of the inclusions shown in Figures 1-8 of the article posted on the s3support.com web site.

Pigmented Particles, Threads and Ribbon-like Structures in Stealth Virus Cultures

Representative photographs of the cytopathic effect occurring in stealth virus cultures are also available on the web site. The repair and reactivation processes are illustrated in Figures 1 and 2 of the published article "Stealth virus culture pigments: a potential source of cellular energy." Exp Mol Pathol. 2003: 74:210-23 . Many of the cell clusters become pigmented and the pigmented material can coalesce into discrete particles, some of which are extruded into the tissue culture medium. Various threads and ribbon-like structures can also develop in stealth virus cultures.

They can show intricate patterning and can exist as either hollow tubes or flat bands. Both by scanning electron microscopy and auto-fluorescence microscopy, the particles can be seen as conglomerates of finer particles. The tread and ribbon-like structures are also auto-fluorescent with wide excitation and emission spectra. The particles can occasionally show magnetic activity which is characterized by a degree of variability in sensitivity and responsiveness that is not seen with inorganic metallic objects. Electron dispersive X-ray (EDX) analysis shows that the particles contain various minerals with individual particles displaying quite distinctive patterns of mineral composition.

The particles can show both electron donating (reducing) and electron accepting (oxidizing) reactions. The former is readily demonstrated using the chromogen MTT as an electron acceptor. It can also occur with reagents such as iodine in alcohol. Oxidation is seen with the appearance of calcium oxalate crystals following the addition of ascorbic acid to medium containing ACE pigments. The particles can also generate gas bubbles when placed in water. A remarkable feature is the variability seen over time with many of these properties. The particles appear to exist in both a "charged" and a "discharged" state. Individual particles will also commonly resonate when exposed to wide band sound frequencies.

Using a sound generator, each particle will commonly exhibit a rather narrow range of movement activating frequencies. Externally applied electromagnetic, fixed and pulsating magnetic energies, and sound waves can show effects on isolated ACE-pigments and on the viability of stealth virus cultures. It is easier to demonstrate cell destructive effects using light, X-ray and magnetic energies, but low intensity energy exposures have clearly benefited some cultures. Both sound and magnetic energies can induce considerable movement of freely floating cell clusters.

ACE Pigments Derived from Stealth Virus Infected Patients.

Similar mineral containing particles have been found in dried perspiration from stealth virus infected patients. They can exhibit rapidly reversible electrostatic properties suggesting internal movements of electrical charge. They are auto-fluorescent and can be both reducing (electron donating) and oxidizing (electron accepting). They can also generate gas bubbles from water.

Erratic movements of the particles in liquid suspensions may account for what earlier investigators have termed pleomorphic microorganisms. The occasional transformation of the particles into thread-like forms is also consistent with the mistaken belief that the supposed bacteria could transform into fungal forms. It is likely that ACE pigments are also responsible for so called delusional parasitosis or Ekbom's syndrome experienced by occasional patients with severe psychiatric illness. They may also explain mistaken reports of head lice in stealth virus infected patients.

Natural Products and Subtle Energies

An assay for the electron shuttling activity of ACE-pigments has been developed and applied to a number of natural products, including a Japanese plant extract and a material designated Enercell. Interesting patterns develop during these reactions that appear to be subject to environmental influences. These reactions are currently being used as a potential sensor for non-conventional forms of energy that may influence their physical and/or chemical properties. Other highly energized natural products can contain microscopic energy rich particles that show remarkable motility and that could easily be mistaken for bacteria.

Although not as well characterized as electromagnetic radiation, most physicists realize that other radiating forms of energy do exist. Included in this category are so called dark energy, phonons, biophotons (chi, orgone) and what is variously referred to as the ether, subtle energy, or zero-point energy. Understanding the potential reciprocal interactions of living organisms and the ether is rendered difficult because of the lack of suitable detection methods.

The restricted patterns of the minerals in individual ACE pigment particles suggested the existence of selective mineral affinity forces that favor the attraction of like substances. Minerals have mainly been studied in inorganic forms. Increasingly, it appears that minerals can exhibit quite different properties when either single atoms or small microclusters. Minerals can also behave differently when incorporated into organic and even silica based complex molecular lattices.

The concepts of orbitally-rearranged monoatomic element ( ORME ), molecular energy transduction with superconducting coherent energy emissions, and gravity defying elements, have been proposed to explain some of the unique features of these altered states of mineral existence. The field of biophysics is currently addressing the potential harmonization of energy patterns within living organisms and even between organisms separated by considerable distances. The experience of various healers would also suggest that conscious thought may be able to alter these harmonizing energy patterns.

Clinical and Agricultural Studies

Given their strong activity in the electron transferring assay system and testimonial evidence for efficacy in various disease states, a number of these natural products have been selected for detailed double blind, placebo controlled studies. Subjects with illnesses potentially attributable to stealth virus infections, and subjects who manifestly are lacking in energy production would be selected. Among the latter group plans are underway to test patients with various wasting syndromes (including cancer cachexia), children with severe diarrhea and asphyxiated newborn infants. Studies on both experimental and livestock animals can similarly be performed.

An advantage of the energy based approach to therapy is that it removes the focus away from using products as a means of enhancing the immune system. The new approach allows for a two way extension of studies to be conducted in an agricultural setting. Thus many products destined for evaluation in human and animal studies can be objectively assessed for their growth enhancement of various plants and crops. Conversely, natural materials that promote the quality of agricultural products may find usefulness in both animals and humans.

Co-ordination of Effort

It would be desirable to have an organizational structure that would encourage open communication among individuals contributing products, performing efficacy assessments and conducting basic research. Sound financial management and good public relations are also essential. The Government, Industry and Major Academic Institutions have, unfortunately, tended to put money-driven self interests above that of the public.

A fledgling non-profit organization termed S3Support has been joined by an Applied BioPhysics Foundation to form the Progressive University and BioPhysics Institute. Its primary goal is to develop and promote a nationwide endeavor to more rapidly bring the enormous benefits of energy based clinical and agricultural science to mankind. This effort can be assisted by increasing the membership of health care providers, farmers, researchers, administrators, public spokespersons, patients and their family members, etc., in the Applied BioPhysics Foundation.